Category Archives: LEVITRA Details

Levitra: How a popular drug works

Levitra has the most beneficial effect in maintaining the erection

What is the principle of action of Levitra

The principle of Levitra is based on inhibiting a chemical that causes the outflow of blood from the penis, returning it from the state of erection. To understand how Levitra works, it is necessary to understand the very principle of the erection. When a man is sexually stimulated, the transmitted neural signals cause the release of a chemical, leading to an increase in blood flow in the penis. In the ordinary state, blood does not flow in such big quantity into the cavernous bodies of the penis. When stimulated, the flow of blood along the arteries fills the penis, squeezing out the outgoing veins, creating pressure and erection. The reverse process occurs when those chemicals are destroyed by another substance in the body called phosphodiesterase type 5 (PDE-5).

Levitra inhibit this PDE-5, due to what substances responsible for the appearance of an erection are preserved, thus, the muscles of the penis do not narrow. This allows the blood to stay, keeping the pressure longer, thereby maintaining the erection.

How quickly it will work and how long it will last

The time it takes for a pill to act can be different for different men. During the research, the pills started to act within an hour. Often, men see the start of Levitra’s work within 30 minutes. The duration of the action may also vary, but, as a rule, it is 4-5 hours.

When and how it can be taken

Levitra should be taken if necessary 1 hour before sexual activity. But not more than 1 pill a day. It is recommended to take the pill with a glass of water. Levitra is resistant to food, so it can be taken with food, however, a large amount of fatty foods can reduce the amount of the drug in the blood, therefore, reduce the effectiveness and duration of the action.

Possible side-effects of Levitra

When you act on the decision to start taking Levitra, it is in your own interests to monitor how your body reacts. For example, among the possible side-effects are dizziness and blurred vision, so it would be unwise to drive your car or operate dangerous machinery until you are confident that there will be no danger to yourself and others. With Levitra, it is better not to drink alcohol at all, or if you cannot avoid it in a social context, drink only a little until you know how your body is likely to react. It is more common to experience adverse side-effects if you have mixed the drug with alcohol. You should also know that the side-effects are more common during hot weather or if you lead a very active sporting life. If any of these possibilities apply to you, make sure that you stand up or get out of bed slowly, otherwise dizziness or a loss of physical co-ordination may cause you an embarrassing fall. Finally, you should not take Levitra and eat grapefruit or drink grapefruit juice. There are chemicals in grapefruit that affect the rate at which you body absorbs a drug into the blood stream. It is safer not to mix Levitra with grapefruit in any form.

Clinical trials and increasing personal experience shows that most men can use Levitra without any adverse side-effects. If side-effects do come, they are usually mild and do not last long. The mild side-effects to look out for include:

  • a flushing or blushing of the face or neck;
  • a headache;
  • an upset stomach, heartburn or nausea;
  • cold symptoms of a stuffed-up or “runny” nose; or
  • back pain.

Should you experience any of the following while engaging in sexual activity, stop immediately and call a doctor if:

  • your erection is painful or lasts for an unnaturally long time;
  • you feel dizzy or faint;
  • your vision is distorted with symptoms ranging from photosensitivity, seeing everything with a blue tinge, being unable to tell the difference between blue and green, to a sudden loss of vision;
  • you hear a ringing sound in your ears or suddenly lose your hearing;
  • you feel nausea, heavy sweating and have difficulty in breathing;
  • you feel tachycardia or palpitations. All sexual activity can strain your heart. In a healthy person, this is not a problem. But if you have any cardiovascular condition, the first symptoms will be chest pain during sexual activity;
  • there is an allergic reaction involving the swelling of your face, throat, and limbs; or
  • you have pain or numbness in your upper body.

These are serious symptoms and you should get urgent help. When seeing you doctor or attending hospital. tell whoever is treating you that you have taken Levitra.

Finally, if you are proposing to take any form of surgery involving the use of anaesthetics, whether medical or dental, you must tell the doctor or dentist that you are taking Levitra.

Dosage and administration

As with all other medicines available on prescription, when taking Levitra you should follow the instructions given by your doctor or as set out in the notes included in the box. Always ask your doctor or pharmacist to explain anything you do not understand. If taking this drug proves a success (which it does in slightly more than 85% of men who take it), you may be tempted to sing its praises to your friends. Talking about this drug is not a problem, but you should not give your tablets to anyone for them to try. The fact that you can take this drug without a problem does not mean that others will be so lucky. Let them seek proper medical advice before taking this medication.

Levitra is supplied in tablet form as 2.5mg, 5mg, 10mg and 20mg doses, which should be taken without food between twenty-five and sixty minutes before you anticipate sexual activity. If it does not produce an erection the first or second time you use it, consult your doctor to see whether you should try an increased dose. You should use Levitra with confidence. In a clinical trial involving about 4,400 men, Levitra produced an improved erection among 85% of the participants the first time the drug was taken. But do remember that Levitra does not produce an erection on its own. An erection is only produced when you experience satisfying sexual stimulation. One of the reasons why men sometimes fail to get an erection is the fear of failure.

If the erection comes but is painful or lasts for an unnaturally long time (a condition called priapism) you should get in touch with your doctor immediately or go to hospital on an emergency basis. A failure to take action in these circumstances may result in your penis being permanently damaged.

In general terms, there are no requirements about eating. But, if you take a pill after eating a big meal, Levitra may be slightly slower than usual to produce its effect — the quantity of food in your stomach slows down the process of absorbing the drug into your blood stream. You should not crush or chew the tablets, but swallow them whole with plenty of water. The usual safe starting dose is 10mg and the normal expectation would be to take one tablet as and when required, and not more than once per day, i.e. you should wait for 24 hours between doses. Some men prefer to establish a routine of taking one tablet every day. Should you forget to take a dose, never double the next dose to “catch up”. It can be dangerous to exceed the daily dose.

As to storage, you should keep the tablets at room temperature in an airtight container. Avoid excess heat and moisture (so do not keep Levitra in the bathroom) and keep it out of the reach of children. As soon as you decide to stop taking Levitra, you should throw away any unused tablets. Similarly, you should dispose of any tablets that are out-of-date. If you are worried about safety in disposing of any drugs, ask your pharmacist.

Before taking Levitra

You should not take Levitra in any of the following situations unless you have first discussed the risks with your doctor. The doctor may want to adjust the dosage of Levitra you take or give you separate treatment for any of the other illnesses or conditions that you may have before you take Levitra.

  • Is there any evidence of a cardiovascular disease including high or low blood pressure, arrhythmia or angina? Perhaps there is a family history of strokes or blood clots. Have you experienced any symptoms suggesting the possibility of a heart attack?
  • Do you have any of the blood cell disorders including leukaemia and sickle cell anaemia, or conditions that may make you bleed without real control including stomach ulcers and the more serious haemophilia?
  • Do you suffer from liver or kidney disease requiring you to be on dialysis?
  • Do you have any physical symptoms including any change to the shape and size of your testicles or your penis? Do you have any localised pain in your groin or when you urinate?
  • Do you have any night blindness, tunnel vision or other eye problems with a genetic origin?
  • Have you ever been advised by a doctor not to have sexual intercourse?

You should be aware of the following problems:

1. Just as Levitra increases the flow of blood in some parts of the body, it can simultaneously decrease the flow of blood to the optic nerve. This has caused a sudden loss of vision in a small number of people taking Levitra. All those affected shared one or more of the following characteristics:

  • tested high for cholesterol levels;
  • suffered from Type 1 or Type 2 Diabetes;
  • had pre-existing hypertension;
  • had pre-existing cardiovascular conditions;
  • were diagnosed with one or more genetic eye conditions;
  • were smokers; and/or
  • were aged 50 years or more.

If you experience a sudden loss of vision after taking Levitra, treat this as a medical emergency and go to a hospital immediately.2. Another very small number of patients have experienced sudden loss of hearing. Again, if this happens to you, treat it as a medical emergency.

3. Do not take Levitra if you are also taking any drug, whether medicinal or recreational, that contains a nitrate, e.g. for the treatment of angina or heart disease. Combining Levitra with a nitrate can cause a sudden loss of blood pressure. You may feel dizzy and faint. In very rare cases, it can cause a stroke or a heart attack. You must also be very cautious if you are taking other prescription medications including:

  • different branded or generic drugs for the treatment of erectile dysfunction. It is natural that you worry about your ability to have sexual intercourse, but taking more than one medication at the same time is an overdose and can be dangerous. Further, unless your doctor specifically allows it, you should not use any of the drugs to treat impotence with a different set of symptoms and causes such as alprostadil.
  • one of the macrolide antibiotics such as clarithromycin or erythromycin;
  • one of the alpha blockers used to treat high blood pressure such as doxazosin and prazosin;
  • one of the drugs used to treat arrhythmia such as amiodarone;
  • one of the drugs used to treat fungal infections such as itraconazole;
  • one of the mood stabilising drugs such as carbamazepine; and
  • any combination of the drugs used to treat HIV infection.

This is not a complete list. There are other drugs that can affect the way in which Levitra works in your body. It is in your own interests to give your doctor a complete list of all the drugs, non-prescription medications, and health and herbal products that you are taking. Then, after starting to take Levitra, do not start to take any new medicine or products (even something as apparently innocent as vitamins) without first consulting your doctor.

4. Levitra is not designed to be taken by women, but some women do experiment. This is not unsafe. But, if you are pregnant, you should seek medical advice. At the time of writing, there is no evidence that Levitra will harm your unborn baby. There is also no evidence that Levitra will get into your breast milk and affect a baby boy. Nevertheless, research continues all the time and you should always ensure that you have the most up-to-date information.

Talking to your doctor about Levitra

In most countries, Levitra is available on prescription. You will also find it over-the-counter in most of the drugstores and you can always buy Levitra online.

Before taking any new prescription medication, it is always advisable to consult your doctor. If you go to see your regular medical practitioner, he or she will have access to your medical records. This saves time because the doctor can review your medical history quickly before responding to your request for treatment.

But this does not relieve you of the need to give up-to-date information about any:

  • additional drugs;
  • health supplements;
  • herbal remedies; and
  • dietary supplements

that you have begun to take since your last visit.If you decide to see a different doctor — perhaps you feel it will be less embarrassing to discuss such delicate issues with a stranger — take your time and give a comprehensive outline of your medical history during the first consultation. The problem you need to address is that a significant number of older drugs have fallen out of patent protection and are now available as generics over-the-counter or from online pharmacies without formal prescription. Similarly, many of the new non-prescription “health” products also contain active chemical compounds. Any time you mix different drugs and other products, there is a risk of adverse reactions. You should try to ensure that there will be no danger if you add Levitra to the mix. Another issue that you should address when you go through your medical history is whether you have any allergies to medications, foods, pollens or other substances. Such allergies can demonstrate a predisposition to be allergic to some classes of drugs.

If you do decide to buy Levitra online without first seeing a doctor, the label and accompanying notes with each pack of Levitra explain the more common medications and products to avoid. In particular, even though you may have performance anxiety and want to ensure that you do not fail to deliver, never give into the temptation to take Levitra at the same time as Viagra or Cialis. This can be a dangerous overdose.

If you are more than fifty-five years old, a full physical check-up is in order. Because of your sexual problems, you may have been less active. If you now take Levitra and suddenly subject your body to physical exertion, there is a risk that you will overexert yourself. The older you are, the greater the need to seek advice before taking Levitra.

Next, you should tell your doctor if you have noticed any physical changes in yourself that might explain the failure of sexual performance. Some men find that their penis or testicles slightly change shape or there may have been an episode of priapism where an erection lasted for an unnaturally long period of time. Events of this kind should be carefully investigated before you begin taking a drug that has been designed to produce a harder erection over a longer period of time.

Finally, we should mention some of the myths that surround Levitra and the other drugs for the treatment of erectile dysfunction. These drugs do not have magic properties. If you have unprotected sex, you are at risk of contracting one of the sexually transmitted diseases (STDs) including HIV infection. The only way to avoid this risk is to use a condom. By definition, the reverse is also true. If you already carry an STD, you will pass it on to your partner if you have sexual intercourse without wearing a condom. And, as a final statement of the obvious, because Levitra is not a condom, you will emit sperm in the usual way, and so may fertilise an egg in your partner unless she is taking independent contraceptive precautions.

You should also note that Pfizer, the pharmaceutical manufacturer that markets Viagra, is currently defending a second law suit alleging that it has improperly marketed its drug as restoring sexual desire in men. The advertising forming the basis of both actions failed to mention erectile dysfunction, did not disclose any of the side-effects, etc. The FDA and other regulatory bodies have licensed the three drugs Levitra, Cialis and Viagra as treatments for erectile dysfunction and not as performance enhancers for healthy men. You should recognise that if you have erection problems, the underlying causes may be Diabetes, high blood pressure or heart disease. The best approach is always to see a doctor for a proper diagnosis and get treatment when treatment is needed. Anything else is a bonus from off-label use.